​​169.  Cho M, Park H-K, Nguyen LP, Nguyen TU, Nguyen DT, In S, et al. (2026) Functional CCR7A-mediated cellular responses are negatively modulated by the splice variant CCR7B. PLoS One 21(8): e0354819. https://doi.org/10.1371/journal.pone.0354819

168. Nguyen, Thai Uy, Su Jeong Kwon, Sunghoon Hurh, Ashok Kale, Jae Min Cho, Hossam Nada, Chang Seong Kim, Peela Induvadana, Beom Jin Park, Kyeong Lee, and et al. 2025. "LMT2368 (1-(4-Chlorophenyl)-3-(3-fluoro-5-(trifluoromethyl)phenyl)urea) Negatively Regulates Inflammation by Inhibiting NLRP3 Inflammasome Activation" Pharmaceutics 17, no. 10: 1241. https://doi.org/10.3390/pharmaceutics17101241

167. Yoo, H., Boo, K.-J., Nguyen, L. P., Hwang, J.-I., Lee, C. S., Yang, S. H., Jeon, S. J.*, Kim, Hong-Rae*, Kim, H*. Exploring Neurokinin-1 Receptor Antagonism for Depression with Structurally Differentiated Inhibitors. Exp. Mol. Med. accepted.

166. Lee, H., Hurh, S., Kang, S., Yoon, J., Hwang, J.-I.*, Logan, D. T.*, Kim, Hong-Rae*. Identification of Chemical Scaffolds for Targeting Ubiquitin-Specific Protease 11 (USP11) through HIgh-throughput Virtual Screening. J. Enz. Inh. Med. Chem. 2025, 40, 2518191.

165. Thai Uy Nguyen, Sunghoon Hurh, Soyeon In, Lan Phuong Nguyen, Minyeong Cho, Kateryna Mykhailova, Hong-Rae Kim, Byung-Joo Ham, Yongseok Choi, Won-Ki Kim, Jong-Ik Hwang " SP-8356 inhibits acute lung injury by suppressing inflammatory cytokine production and immune cell infiltration" Int Immunopharmacol, Volume 131, 20 April 2024, 111847

164. Lan Phuong Nguyen, Minyeong Cho, Thai Uy Nguyen, Hee-Kyung Park, Huong Thi Nguyen, Kateryna Mykhailova, Sunghoon Hurh, Hong-Rae Kim, Jae Young Seong, Cheol Soon Lee, Byung-Joo Ham, Jong-Ik Hwang " Neurokinin-2 receptor negatively modulates substance P responses by forming complex with Neurokinin-1 receptor"  Cell Biosci 13, 212 (2023)

163.  Hee-Kyung Park, Lan Phuong Nguyen, Thai Uy Nguyen, Minyeong Cho, Huong Thi Nguyen, Sunghoon Hurh, Hong-Rae Kim, Jae Young Seong, Cheol Soon Lee, Byung-Joo Ham, Jong-Ik Hwang "The N-terminus of CXCR4 splice variants determines expression and functional properties" PLoS One. 2023; 18(5): e0283015. 

162. Huong Thi Nguyen, Sunghoon Hurh, Lan Phuong Nguyen, Thai Uy Nguyen, Hee-Kyung Park, Jae Young Seong, Cheol Soon Lee, Byung-Joo Ham, and Jong-Ik Hwang "Functional Analysis of CXCR3 Splicing Variants and Their Ligands Using NanoBiT-Based Molecular Interaction Assays" Mol. Cells 2023; 46(5): 281-297

161. Hee-Kyung Park, Yun Hee Na, Huong Thi Nguyen, Lan Phuong Nguyen, Sunghoon Hurh, Jae Young Seong, Cheol Soon Lee, Byung-Joo Ham, Jong-Ik Hwang "Analysis of CCR2 splice variant expression patterns and functional properties"  Cell & bioscience volume 12, Article number: 59 (2022)  

160. Huong Thi Nguyen, Arfaxad Reyes-Alcaraz, Hyo Jeong Yong, Lan Phuong Nguyen, Hee-Kyung Park, Asuka Inoue, Cheol Soon Lee, Jae Young Seong & Jong-Ik Hwang "CXCR7: a β-arrestin-biased receptor that potentiates cell migration and recruits β-arrestin2 exclusively through Gβγ subunits and GRK2" Cell & Bioscience volume 10, Article number: 134 (2020) 

159. Lan Phuong Nguyen, Huong Thi Nguyen, Hyo Jeong Yong, Arfaxad Reyes-Alcaraz, Yoo-Na Lee, Hee-Kyung Park, Yun Hee Na, Cheol Soon Lee, Byung-Joo Ham, Jae Young Seong, Jong-Ik Hwang "Establishment of a NanoBiT-Based Cytosolic Ca 2+ Sensor by Optimizing Calmodulin-Binding Motif and Protein Expression Levels" Mol. Cells 2020; 43(11): 909~920  

158. Hyo Jeong Yong, Nui Ha, Eun Bee Cho, Seongsik Yun, Hyun Kim, Jong-Ik Hwang and Jae Young Seong “The unique expression profile of FAM19A1 in the mouse brain and its association with hyperactivity, long-term memory and fear acquisition”  Scientific Reports 2020(10:3969)   2020.3

157. Yoo-Na Lee, Arfaxad Reyes-Alcaraz, Seongsik Yun, Cheol Soon Lee, Jong-Ik Hwang, Jae Young Seong “Exploring the molecular structures that confer ligand selectivity for galanin type II and III receptors”  Plos One 15(3) e0230872    2020,03,14

156. Anu Shahapal, Eun Bee Cho, Hyo Jeong Yong, Inyoung Jeong, Hoyun Kwak, Jae Keun Lee, Wonkyum Kim, Bongcheol Kim, Hae-Chul Park, Won Suk Lee, Hyun Kim, Jong-Ik Hwang and Jae Young Seong “FAM19A5 Expression During Embryogenesis and in the Adult Traumatic Brain of FAM19A5-LacZ Knock-in Mice” Frontiers in Neuroscience 2019, 08, 30 13, 917(1-15) 

155. Sunam Mander, Dong Hwi Kim, Huong Thi Nguyen, Hyo Jeong Yong, Kisoo Pahk, Eun-Yeong Kim, Kiho Lee, Jae Young Seong, Won-Ki Kim, and Jong-Ik Hwang “SP-8356, a (1S)-(-)-verbenone derivative, exerts in vitro and in vivo anti-breast cancer effects by inhibiting NF-kB signaling” Scientific Reports, 2019, 4. 29  9;6595  1-11

154. Seongsik Yun, Arfaxad Reyes-Alcaraz, Yoo-Na Lee, Hyo Jeong Yong, Jeewon Choi, Byung-Joo Ham, Jong-Woo Sohn, Dong-Hoon Kim, Gi Hoon Son, Hyun Kim, Soon-Gu Kwon, Dong Sik Kim, Bong Chul Kim, Jong-Ik Hwang and Jae Young Seong “Spexin-Based Galanin Receptor Type 2 Agonist for Comorbid Mood Disorders and Abnormal Body Weight” Frontiers in Neuroscience 2019. 4. 18 vol 13 article 391 1-11

153.  Arfaxad Reyes-Alcaraz, Yoo-Na Lee, Seongsik Yun, Jong-Ik Hwang and Jae Young Seong “Conformational signatures in β-arrestin2 reveal natural biased agonism at a G-protein-coupled receptor”  Communications Biology 2018, 1:128

152. Seungho Choi, Jong Kyu Woo, Yeong-Su Jang, Ju-Hee Kang, Jong-Ik Hwang, Je Kyung Seong, Yeo Sung Yoon and Seung Hyun Oh “Ninjurin1 Plays a Crucial Role in Pulmonary Fibrosis by Promoting Interaction between Macrophages and Alveolar Epithelial Cells” Scientific Reports, 2018, 12   8: 17542, 1-14+

151. Sunam Mander, Dong-Joo You, Sumi Park, Dong Hwi Kim, Hyo Heong Yong, Dong-Sik Kim, Curie Ahn, Yun-Hee Kin, Jae Young Seong, and Jong-Ik Hwang  “Nafamostat mesilate negatively regulates the metastasis of triple-negative breast cancer cells” Archives of Pharmacal Research, 2018,02,  41:229-242

150.  Geon A. Kim, Jun-Xue Jin, Sanghoon Lee, Anukul Taweechaipaisankul, Hyun Ju Oh, Jong-Ik Hwang, Curie Ahn, Islam M. Saadeldin, and Byeong Chun Lee “ Postneonatal Mortality and Liver Changes in Cloned Pigs Associated with Human Tumor Necrosis Factor Receptor I-Fc and Human Heme Oxygenase-1 Overexpression” BioMed Research International,  2017, 5276576  10pages  4/19

149. Geon A. Kim, Eun Mi Lee, Jun-Xue Jin, Sanghoon Lee, Anukul Taweechaipaisankul, Jong Ik Hwang, Zahid Alam, Curie Ahn, Byeong Chun Lee “Generation of CMAHKO/GTKO/ shTNFRI-Fc/HO-1 quadruple gene modified pigs” Transgenic Research 26, 4, 435-445  /26

148. Cho Rong Park, Dong-Joo You, Sumi Park, Sunam Mander, Da-Eun Jang, Su-Cheong Yeom, Seong-Hyun Oh, Curie Ahn, Sang Heon Lee, Jae Young Seong & Jong-Ik Hwang  2016.12 “The accessory proteins REEP5 and REEP6 refine CXCR1-mediated cellular responses and lung cancer progression” Scientific Reports 6: 39041, 1-13

147. Sunghoon Hurh, Bohae Kang, Inho Choi, Baumrae Cho, Eun Mi Lee, Hwajung Kim, Yun Shin Chung, Jong Cheol Jeong, Jong-Ik Hwang, Jae Young Kim, Byeong Chun Lee, Charles D. Surh, Jaeseok Yang, Curie Ahn 2016.7 “Human antibody reactivity against xenogeneic N-glycolylneuraminic acid and galactose--1,3-galactose antigen” Xenotransplantation 23, 4, 279-292

146. Yeong-Su Jang, Ju-Hee Kang, Jong Kyu Woo, Hwan Mook Kim, Jong-Ik Hwang, Sang-Jin Lee, Ho-Young Lee and Seung Hyun Oh 2016.7 ” Ninjurin1 suppresses metastatic property of lung cancer cells through inhibition of interleukin 6 signaling pathway” International Journal of Cancer 139, 383-395

145. Dong-Joo You, Sunam Mander, Cho Rong Park, Okjae Koo, Cheolju Lee, Seong-Hyun Oh, Curie Ahn, Jae Young Seong, and Jong-Ik Hwang 2016.6 “ NME1L Negatively Regulates IGF1-Dependent Proliferation of Breast Cancer Cells” Journal of Cellular Biochemistry 117, 1454-1463

144.  Dong-Joo You, Cho Rong Park, Sunam Mander, Curie Ahn, Jae Young Seong, and Jong-Ik Hwang 2016.5 “Characterization of Functional Domains in NME1L Regulation of NF-kB Signaling” Molecules and Cells 39(5) 403-409

143. Jong Kyu Woo, Yeong-Su Jang, Ju-Hee Kang, Jong-Ik Hwang, Je Kyung Seong, Sang-Jin Lee, Sejin Jeon, Goo Taeg Oh, Ho-Young Lee, Seung Hyun Oh 2016.4 “ Ninjurin1 inhibits colitis-mediated colon cancer development and growth by suppression of macrophage infiltration through repression of FAK signaling” Oncotarget 7(20) 29592-29604

142. Ji-Jing Yan, Hye-Jeong Yeom, Jong Cheol Jeong, Jae-Ghi Lee, EunWon Lee, Bumrae Cho, Han Sin Lee, Su Jin Kim, Jong-Ik Hwang, Sung Joo Kim, Byeong-Chun Lee, Curie Ahn, Jaeseok Yang 2016.2 “Beneficial effects of the transgenic expression of human sTNF-αR-Fc and HO-1 on pig-to-mouse islet xenograft survival” Transplant Immunology 34, 25-32

141. Arfaxad Reyes-Alcaraz, Yoo-Na Lee, Gi Hoon Son, Nam Hoon Kim, Dong-Kyu Kim, Seongsik Yun, Dong-Hoon Kim, Jong-Ik Hwang & Jae Young Seong 2106.2 “Development of Spexin-based Human Galanin Receptor Type IISpecific Agonists with Increased Stability in Serum and Anxiolytic Effect in Mice” Scientific Reports 6:21453

140. H.-S. Lee, J.-G. Lee, H.J. Yeom, Y.S.Chung, B. Kang, S. Hurh, B. Cho, H. Park, J.I. Hwang, J.B. Park, C. Ahn, S.J. Kim, and J. Yang 2016.1 “The Introduction of Human Heme Oxygenase-1 and Soluble Tumor Necrosis Factor-a Receptor Type I With Human IgG1 Fc in Porcine Islets Prolongs Islet Xenograft Survival in Humanized Mice” American Journal of Transplantation 16, 44-57

139. Dong-Joo You, Cho Rong Park, Michael Furlong, Okjae Koo, Cheolju Lee, Curie Ahn, Jae Young Seong, Jong-Ik Hwang 2015.11 “Dimer of arfaptin 2 regulates NF-κB signaling by interacting with IKKβ/NEMO and inhibiting IKKβ kinase activity” Cellular Signalling 27, 2173-2181

138. Seongsik Yun, Michael Furlong, Mikang Sim, Minah Cho, Sumi Park, Eun Bee Cho, Arfaxad Reyes-Alcaraz, Jong-Ik Hwang, Jaebum Kim, and Jae Young Seong 2015.11 “Prevertebrate Local Gene Duplication Facilitated Expansion of the Neuropeptide GPCR Superfamily” Molecular Biology and Evolution 32(11), 2803-2817

137. Hwajung Kim, Wayne J. Hawthorne, Hee Jung Kang, Yoo Jin Lee, Jong-Ik Hwang, Sunghoon Hurh, Han Ro, Jong Cheol Jeong, Bumrae Cho, Jaeseok Yang and Curie Ahn 2015. 7 “Human thrombomodulin regulates complement activation as well as the coagulation cascade in xeno-immune response” Xenotransplantation 22, 260-272

136. Mi-Jin Moon, Yoo-Na Lee, Sumi Park, Arfaxad Reyes-Alcaraz, Jong-Ik Hwang, Robert Peter Millar, Han Choe, and  Jae Young Seong  2015. 2  “Ligand Binding Pocket Formed by Evolutionarily Conserved Residues in the Glucagon-like Peptide-1 (GLP-1) Receptor Core Domain” J. Biol. Chem. 290, 5696-5706Mi Jin Moon, Yoo-Na Lee, Sumi Park, Arfaxad Reyes-Alcaraz, Jong-Ik Hwang, Robert Peter Millar, Han Choe, and  Jae Young Seong  2015. 2 “Ligand Binding Pocket Formed by Evolutionarily Conserved Residues in the Glucagon-like Peptide-1 (GLP-1) Receptor Core Domain” J. Biol. Chem. 290, 5696-5706